What is the basolateral nucleus of the amygdala?

What is the basolateral nucleus of the amygdala?

Based on its established role in emotions and emotional learning, the basolateral nucleus of the amygdala (BLA) is a structure likely to modulate learning after stress. The BLA is critically involved in the stress-induced modulation of classical conditioning (Neufeld and Mintz, 2001; Rodríguez Manzanares et al., 2005).

What does the basolateral complex of the amygdala do?

The basolateral complex of the amygdala (ABL) is involved in processing information about stimulus motivational value.

What is basolateral membrane?

Definition. The basolateral cell membrane is the fraction of the plasma membrane at the basolateral side of the cell, which faces adjacent cells and the underlying connective tissue.

Where is the basolateral nucleus?

Basolateral nucleus (BL) is also called basal nucleus. It locates ventrally to the LA and includes three subdivisions, i.e., rostral magnocellular subdivision, caudal intermediate and parvicellular subdivisions. The last two are densely innervated by LA. BL plays an integral role in anxiety.

What does basolateral side mean?

Medical Definition of basolateral : situated below and toward the side : located in or on the base and one or more sides Epithelia permit selective and regulated flux from apical to basolateral surfaces …—

What is the basolateral side of the cell?

The basolateral membrane of a polarized cell is the part of the plasma membrane that forms its basal and lateral surfaces, distinct from the apical (or lumenal) surface. This is particularly evident in epithelial cells, but also describes other polarized cells, such as neurons.

How does the hippocampus affect the amygdala?

From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits. Emotion influences various cognitive processes, including learning and memory. The amygdala is specialized for input and processing of emotion, while the hippocampus is essential for declarative or episodic memory.

Is basolateral the same as basal?

“Basolateral membrane” is a compound phrase referring to the terms basal (base) membrane and lateral (side) membrane, which, especially in epithelial cells, are essentially functionally identical in composition and activity.

What is basolateral and apical?

In the context of renal tubule physiology, the term basolateral membrane or serosal membrane refers to the cell membrane which is oriented away from the lumen of the tubule, whereas the term luminal membrane or apical membrane refers to the cell membrane which is oriented towards the lumen.

Is the amygdala next to the hippocampus?

The amygdala is a complex structure of cells nestled in the middle of the brain, adjacent to the hippocampus (which is associated with memory formation). The amygdala is primarily involved in the processing of emotions and memories associated with fear.

Where is the hippocampus located?

temporal lobe
Hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. It is a plastic and vulnerable structure that gets damaged by a variety of stimuli.

What are the basolateral amygdala subregions?

Basolateral amygdala groups are divided into three subregions as described in text. Area in orange is lateral nucleus (L), area in pink is basolateral nucleus (BL), and the area in blue is basomedial nucleus (BM).

Does the basolateral amygdala nucleus respond to appetitive conditioned stimuli?

Basolateral amygdala nucleus responses to appetitive conditioned stimuli correlate with variations in conditioned behaviour. Nat. Commun. 7:12275. doi: 10.1038/ncomms12275

What part of the brain is the amygdala?

The amygdala is considered to be a part of the limbic system within the brain and is key to how we process strong emotions like fear or pleasure.

How many nuclei are in the amygdala?

The amygdala contains at least 13 nuclei (masses of nerve cells), which are typically divided into three primary groups: 4 1 Lateral (side) nucleus and basal (bottom) nucleus, also known as the basolateral nucleus 2 Centromedial (center midline) nucleus 3 Cortical (outer layer of cerebrum)