What does flus mean on thyroid biopsy?

What does flus mean on thyroid biopsy?

Atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS) are a major part of the indeterminate category. Most of these patients undergo a repeat biopsy and a large number of patients undergo surgical removal of their thyroid nodules for a definitive diagnosis.

What does flus mean in thyroid?

Atypia of Undetermined Significance (AUS) / Follicular Lesion of Undetermined Significance (FLUS)

Condition or disease Intervention/treatment
Diagnoses Disease Behavioral: Determination of risk of malignancy of these thyroid lesions

Is Bethesda Category 2 cancerous?

For instance, the recommendation for clinical follow-up for Bethesda Category II (benign) is based on a 0–3% risk of malignancy, while the recommendation for surgery for Bethesda Category V (suspicious for malignancy) is based on a 60–75% risk (5,6).

What is atypia of undetermined significance follicular lesion of undetermined significance?

Atypia of undetermined significance/follicular lesions of undetermined significance (AUS/FLUS) refers to an intermediate histologic category of thyroid nodules in The Bethesda System for Reporting Thyroid Cytopathology.

What percent of thyroid biopsies are cancerous?

Thyroid nodule: an abnormal growth of thyroid cells that forms a lump within the thyroid. While most thyroid nodules are non-cancerous (Benign), ~5% are cancerous.

What is Category 4 thyroid nodule?

Bethesda category IV nodules are described as follicular neoplasm or suspicious for follicular neoplasm (FN/SFN).

Does Bethesda 3 require surgery?

Among the cases classified as Bethesda category III (n = 510), 75 (14.7%) underwent immediate surgery, 133 (26.1%) underwent repeat FNAC in 1–3 months, and 302 (59.2%) underwent ultrasonography monitoring at 3-month intervals to measure the size and content of the nodule.

What does Bethesda Category 5 mean?

Biopsy results can fall within one of six categories as defined by the Bethesda system for reporting FNA cytopathology results: I (non-diagnostic), II (benign), III (atypia of undetermined significance/follicular lesion of undetermined significance), IV (follicular neoplasm), V (suspicious for malignancy), and VI ( …

What is a Category 3 thyroid nodule?

Introduction: The Bethesda System classifies suspicious thyroid nodules or those with a large size after fine-needle aspiration (FNA) depending on the risk of malignancy through its cytology study. Bethesda category 3 (B3) implies atypia of uncertain significance or follicular lesion of undetermined significance.

What is follicular variant of papillary thyroid carcinoma?

Follicular variant of papillary thyroid carcinoma is a histological variant of papillary carcinoma thyroid which has follicular architecture but nuclear features are classical of papillary carcinoma thyroid. It is associated with a higher incidence of extrathyroidal tumor invasion and regional lymphadenopathy.

Is a 10mm thyroid nodule big?

They all recognize that in radiation-exposed patients, the size of a thyroid nodule alone is an inadequate predictor of the risk of malignancy and suggest that all nodules, including the small ones (<10 mm), should undergo fine-needle aspiration (FNA) evaluation.